12/20/2016 · The Xpert ® MTB/RIF ( Xpert ) assay is a rapid PCR-based assay for the detection of Mycobacterium tuberculosis complex DNA (MTBc) and mutations associated with rifampin resistance (RIF). An updated version introduced in 2011, the G4 Xpert , included modifications to probe B and updated analytic software. An analytical study was performed to assess Xpert .
In summary, the Xpert MTB/RIF G4 assay was developed to increase assay robustness and mitigate against potential false resistant rifampin susceptibility results. The analytical studies described above show that: The G4 assay reduces the risk of false rifampin susceptibility results due to anneal temperature abnormalities.
FIND report: performance of Xpert MTB/RIF version G4 assay . FIND, Geneva, Switzerland. 6. Steingart KR, Sohn H, Schiller I, Kloda LA, Boehme CC, Pai M, Dendukuri N. 2013. Xpert (R) MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults.
12/20/2016 · BACKGROUND: The Xpert ® MTB/RIF ( Xpert ) assay is a rapid PCR-based assay for the detection of Mycobacterium tuberculosis complex DNA (MTBc) and mutations associated with rifampin resistance (RIF). An updated version introduced in 2011, the G4 Xpert , included modifications to probe B and updated analytic software.
An evaluation of the Xpert MTB/RIF assay and detection of false-positive rifampicin resistance in Mycobacterium tuberculosis. … .2012.06.013. 5. Foundation for Innovative New Diagnostics.2011. FIND report: per-formance of Xpert MTB/RIF version G4 assay . FIND, Geneva, Switzer-land. 6. Steingart KR, Sohn H, Schiller I, Kloda LA, Boehme CC, Pai …
Performance of the G4 Xpert ® MTB/RIF assay for the …
Performance of the G4 Xpert ® MTB/RIF assay for the …
Performance of the G4 Xpert ® MTB/RIF assay for the …
Performance of the G4 Xpert ® MTB/RIF assay for the …
Background: There are limited data about Xpert -Ultra performance in different settings, in HIV-infected persons, in those with a history of previous TB, and with trace readouts. Methods: We evaluated the relative accuracy of Xpert – MTB/RIF and Xpert -Ultra in 272 selected but well-characterized archived sputum samples. Of these, 168 were culture-positive (64/168 smear.
2/1/2014 · FIND report: performance of Xpert MTB/RIF version G4 assay . FIND, Geneva, Switzerland. 6. ? Steingart KR, Sohn H, Schiller I, Kloda LA, Boehme CC, Pai M, Dendukuri N. 2013. Xpert (R) MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst. Rev. 1: CD009593. doi: …
4. Davis JL, et al. Impact of GeneXpert MTB/RIF on patients and tuberculosis programs in a low-burden setting. a hypothetical trial. Am J Respir Crit Care Med. 2014 Jun 15189(12):1551-9. 5. Lippincott CK, et al. Xpert MTB/RIF Assay Shortens Airborne Isolation for Hospitalized Patients With Presumptive Tuberculosis in the United States.
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Significant reduction of non-reportable results for Xpert MTB/RIF G4 assay ( G4 ). No 5011 errors seen for G4 . Accuracy of G4 Assay Maintained Overall Accuracy of Xpert MTB/Rif G3 assay versus G4 assay Sensitivity in C+ Specificity in S-C-Rif-R Sensitivity Rif-S Specificity G3 82.6% (142/172) [76 -87] 98.8% (242/245) [96 -100] 100.0%
